However, in contrast to earlier Iressa findings, the study showed that there was no additional survival benefit for patients who expressed an elevated level of the epidermal growth factor receptor (EGFR) mutation.

The Iressa in Non-small cell lung cancer Trial Evaluating REsponse and Survival versus Taxotere (INTERST) study, published today in The Lancet, represents a paradigm shift for the treatment of the disease, according to lead author Edward S. Kim, M.D., assistant professor in ...

"This is a different concept in terms of how to address heart disease. The classic thinking is to replace a valve, or place a bypass graft. Traditionally, when the heart gets injured, there's dead tissue, and we work our way around it surgically, even replacing the heart with a transplant," explains principal investigator Joseph Woo, MD, Director of the Minimally Invasive and Robotic Cardiac Surgery Program at Penn and Assistant Professor of Surgery. "So we asked, 'What would b...

Fatigue is a common complaint in the general population and, anecdotally, common among cancer patients. Comparative fatigue studies between the two populations, however, have been marred by methodological shortcomings, such as poorly matched controls and patient populations. The studies do not consistently agree whether or not fatigue is a more common complaint among cancer patients compared to the general population.

Dr. Paul Jacobsen from the Moffitt Cancer Center in Tampa, Florida...

In the September issue of Archives of General Psychiatry, a team based at the University of Chicago Medical Center show that almost 40 percent of participants in family-based treatment had stopped binging and purging compared to only18 percent of those who received supportive psychotherapy, the standard therapy.

Six-months after treatment, almost 30 percent of participants who received family-based treatment were still abstinent compared to only 10 percent of participants who recei...

These startling scientific discoveries illuminate the emerging field of epigenetics, in which single nutrients, toxins, behaviors or environmental exposures of any sort can silence or activate a gene without altering its genetic code in any way.

Rather, the environmental exposure triggers a chemical change in the body or brain that mobilizes a group of molecules – called a methyl group. The methyl group attaches to the control segment of a gene and either silences – or alt...

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